Stealing VEGF from Thy Neighbor

Stealing VEGF from Thy Neighbor

The distribution and patterning of blood vessels is controlled by vascular endothelial growth factor (VEGF), which is precisely regulated throughout its life cycle. Okabe et al. show that VEGF is titrated away from the endothelium by adjacent neurons via endocytosis, regulating density and trajectory of blood vessels.

Don't love thy nearest neighbor

Learn From Thy Neighbor: Parallel-Chain Adaptive MCMC

Starting with the seminal paper of Haario, Saksman and Tamminen (Haario et al. (2001)), a substantial amount of work has been done to validate adaptive Markov chain Monte Carlo algorithms. In this paper we focus on two practical aspects of adaptive Metropolis samplers. First, we draw attention to the deficient performance of standard adaptation when the target distribution is multi-modal. We pr...

Learn From Thy Neighbor: Parallel-Chain and Regional Adaptive MCMC

Starting with the seminal paper of Haario, Saksman and Tamminen (Haario et al. (2001)), a substantial amount of work has been done to validate adaptive Markov chain Monte Carlo algorithms. In this paper we focus on two practical aspects of adaptive Metropolis samplers. First, we draw attention to the deficient performance of standard adaptation when the target distribution is multi-modal. We pr...

Lean From Thy Neighbor: Stochastic & Adversarial Bandits in a Network

An individual’s decisions are often guided by those of his or her peers, i.e., neighbors in a social network. Presumably, being privy to the experiences of others aids in learning and decision making, but how much advantage does an individual gain by observing her neighbors? Such problems make appearances in sociology and economics and, in this paper, we present a novel model to capture such de...